Tumor Protein P53 (TP53) (C-Term) Peptide
TP53
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511296
Quick Overview for Tumor Protein P53 (TP53) (C-Term) Peptide (ABIN5511296)
Target
p53 (TP53)
(Tumor Protein P53 (TP53))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LNEALELKDA QAGKEPGGSR AHSSHLKSKK GQSTSRHKKL MFKTEGPDSD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-P53 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Background
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This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons.
Alias Symbols: TP53,P53,
Protein Size: 393 -
Gene ID
- 7157
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UniProt
- P04637
Target
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